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Volume 35 , Issue 3
May/June 2015
Pages 345–353

Treatment of Severe Mucogingival Defects with a Combination of Strip Gingival Grafts and a Xenogeneic Collagen Matrix: A Prospective Case Series Study

Istvan A. Urban, DMD, MD, PhD/Jaime L. Lozada, DMD/Katalin Nagy, DDS, PhD/Mariano Sanz, MD, DDS

PMID: 25909521
DOI: 10.11607/prd.2287

Large areas of mucogingival alterations may result from advanced regenerative procedures. This prospective case series study was performed to introduce and evaluate a surgical approach that combines the strip gingival graft technique with the use of a xenogeneic collagen matrix. The primary outcome measurement was the increase in keratinized tissue width from baseline to 12 months postprocedure. Twenty patients were enrolled, and they all completed the 12-month evaluation. All treated sites exhibited a significant gain in keratinized tissue at 12 months, with a mean width of 6.33 mm (SD: 2.16), while there was a 43% contraction of the grafted area at 6 months. Tissue dimensions remained stable between 6 and 12 months. The use of the combination graft was well accepted by the patients, with minimal morbidity according to the patients’ low self-reported pain and the low utilization of pain medication.

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